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Meaningful changes for the Oxford hip and knee scores after joint replacement surgery
Beard DJ, Harris K, Dawson J, et al. Journal of clinical epidemiology 2015 · PMID 25441700 · doi:10.1016/j.jclinepi.2014.08.009
Cohort studyPrognosisResearch, statistics & guidelinesCitation checked
- Question
- What change in Oxford hip and knee scores after joint replacement is meaningful to patients?
- Design
- Secondary analysis of the national NHS PROMs dataset using anchor-based and distribution-based methods.
- Patients
- Large national cohorts of patients listed for primary hip or knee replacement in the NHS PROMs programme.
- Intervention
- Anchor-based estimation using patient-reported global change
- Comparison
- Distribution-based estimates
- Primary outcome
- Minimal important change and minimal important difference for OHS and OKS
- Key result
- Group-level minimal important change was roughly 11 points for the OHS and 9 for the OKS (about 8 and 7 points for individual patients), whereas the between-group minimal important difference for trials was about 5 points for both scores.
- Limitations
- Thresholds vary with the method and anchor used and the population studied, so a single cut-off should not be applied rigidly.
- Impact on practice
- These values are used to power UK arthroplasty trials and to judge whether a statistically significant difference in Oxford scores is clinically relevant.