← Evidence libraryPreperitoneal pelvic packing
Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift.
Cothren CC, Osborn PM, Moore EE, et al. The Journal of trauma 2007 · PMID 17426537 · doi:10.1097/ta.0b013e31803c7632
Cohort studyManagementPelvis & acetabulumCitation checked
- Question
- Does a protocol of preperitoneal pelvic packing with external fixation control haemorrhage and reduce mortality in haemodynamically unstable pelvic fractures?
- Design
- Prospective single-centre cohort from Denver Health with comparison against historical controls.
- Patients
- Patients with pelvic fractures who remained haemodynamically unstable despite resuscitation.
- Intervention
- Preperitoneal pelvic packing plus pelvic external fixation, with angiography reserved for ongoing bleeding
- Comparison
- Historical angiography-first protocol
- Primary outcome
- Mortality from acute haemorrhage and transfusion requirement
- Key result
- Packing was associated with rapid haemorrhage control, reduced post-procedure transfusion and low mortality from acute haemorrhage, with only a minority needing subsequent angioembolisation.
- Limitations
- Single-centre, non-randomised design with historical controls; results depend on a system able to deliver packing immediately.
- Impact on practice
- Established preperitoneal packing as an alternative or adjunct to angioembolisation for the unstable patient, now part of UK major trauma centre haemorrhage pathways alongside binders and interventional radiology.