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NZ registry laminar flow and space suits

Does the use of laminar flow and space suits reduce early deep infection after total hip and knee replacement?: the ten-year results of the New Zealand Joint Registry.

Hooper GJ, Rothwell AG, Frampton C, et al. The Journal of bone and joint surgery. British volume 2011 · PMID 21196549 · doi:10.1302/0301-620x.93b1.24862

Registry studyPreventionOperative technique & equipmentCitation checked
Question
Are laminar flow theatres and space suits associated with lower early revision for deep infection after hip and knee replacement?
Design
Ten-year analysis of the New Zealand Joint Registry.
Patients
Primary total hip and knee replacements recorded in the New Zealand Joint Registry.
Intervention
Laminar flow ventilation and/or space suits
Comparison
Conventional ventilation without space suits
Primary outcome
Revision for deep infection within six months
Key result
Laminar flow and space suits were not associated with lower early revision for deep infection; early infection revision was significantly higher with their use in both hip and knee replacement, independent of age, diagnosis and operating time.
Limitations
Registry data cannot control for case mix and theatre behaviour, and only early revision for infection was captured.
Impact on practice
It challenged the assumption that modern laminar flow and space suits lower infection risk and is regularly cited in exam discussions of theatre ventilation. UK practice still uses laminar flow for arthroplasty.
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