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NJR stemmed MoM failure

Failure rates of stemmed metal-on-metal hip replacements: analysis of data from the National Joint Registry of England and Wales.

Smith AJ, Dieppe P, Vernon K, et al. Lancet (London, England) 2012 · PMID 22417410 · doi:10.1016/s0140-6736(12)60353-5

Registry studyPrognosisHip arthroplastyCitation checked
Question
How do revision rates of stemmed metal-on-metal total hip replacements compare with other bearing surfaces?
Design
Analysis of the National Joint Registry of England and Wales.
Patients
Patients with primary stemmed total hip replacements recorded in the NJR, including metal-on-metal bearings.
Intervention
Stemmed metal-on-metal bearings
Comparison
Metal-on-polyethylene and ceramic bearings
Primary outcome
Implant revision
Key result
Stemmed metal-on-metal hips had significantly poorer survival than other bearings, with larger heads failing earlier, whereas larger heads improved survival for ceramic-on-ceramic bearings; younger women with large metal-on-metal heads had particularly high revision rates.
Limitations
Registry data cannot fully adjust for confounding by surgeon, implant design or case mix, and revision is an imperfect proxy for failure.
Impact on practice
Contributed to the near abandonment of metal-on-metal THR and to MHRA surveillance of patients with these implants, including blood metal ion testing.
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