OrthoQB

Evidence library

The trials, meta-analyses and guidelines that shape orthopaedic diagnosis and management, each summarised in one screen: what it asked, what it found, and how it changed practice. Every citation is checked against PubMed.

AllDiagnosisManagementPrognosisPrevention
All topicsShoulderElbowWristHandPeripheral nerveHip (young adult & sports)Hip arthroplastyKnee soft tissue & sportsKnee arthroplastyFoot & ankleSpineUpper limb traumaPelvis & acetabulumLower limb traumaMajor trauma & polytraumaFracture clinic & non-operative carePost-op care & complicationsOperative technique & equipmentInfectionPaediatricsTumoursRheumatology & metabolic boneBasic scienceResearch, statistics & guidelines
Cochrane tourniquet TKA reviewThe Cochrane database of systematic reviews 2020
Tourniquet use for knee replacement surgery.
Tourniquet use was associated with a higher risk of serious adverse events (such as venous thromboembolism and infection) and slightly worse early postoperative pain, with little or no functional benefit.
Systematic review / meta-analysisManagementKnee arthroplasty
TOPKATLancet (London, England) 2019
The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.
There was no significant difference in Oxford Knee Score at 5 years, with similar reoperation and complication rates; partial knee replacement was more cost-effective and showed small advantages in some secondary measures.
Randomised trialManagementKnee arthroplasty
Robotic-arm assisted TKA (Kayani)The bone & joint journal 2018
Robotic-arm assisted total knee arthroplasty is associated with improved early functional recovery and reduced time to hospital discharge compared with conventional jig-based total knee arthroplasty: a prospective cohort study.
Robotic TKA was associated with significantly less early postoperative pain and analgesia requirement, faster attainment of straight leg raise and range of motion, and shorter hospital stay.
Cohort studyManagementKnee arthroplasty
Skou TKR vs non-surgical RCTThe New England journal of medicine 2015
A Randomized, Controlled Trial of Total Knee Replacement.
TKR plus non-surgical treatment produced significantly greater improvement in pain, function and quality of life at 12 months, but with more serious adverse events; most in the non-surgical group improved and many had not undergone TKR by 1 year.
Randomised trialManagementKnee arthroplasty
Kinematic vs mechanical alignment RCT (Dossett)The bone & joint journal 2014
A randomised controlled trial of kinematically and mechanically aligned total knee replacements: two-year clinical results.
Kinematically aligned knees had significantly better pain relief, Oxford, WOMAC and Knee Society scores and greater flexion at 2 years than mechanically aligned knees.
Randomised trialManagementKnee arthroplasty
KAT patellar resurfacingThe Journal of bone and joint surgery. American volume 2011
Patellar resurfacing in total knee replacement: five-year clinical and economic results of a large randomized controlled trial.
There was no significant difference in Oxford Knee Score or any other outcome at 5 years, including reoperation and later patella-related surgery, and total healthcare costs did not differ between resurfacing and non-resurfacing.
Randomised trialManagementKnee arthroplasty