VITAL fracture analysisThe New England journal of medicine 2022
Supplemental Vitamin D and Incident Fractures in Midlife and Older Adults
Vitamin D3 did not significantly reduce total, non-vertebral or hip fractures compared with placebo.
Randomised trialPreventionRheumatology & metabolic bone
SCOOPLancet (London, England) 2018
Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial
Screening increased uptake of osteoporosis medication but did not significantly reduce the primary outcome of all osteoporosis-related fractures; hip fractures, a prespecified secondary outcome, were reduced.
Randomised trialPreventionRheumatology & metabolic bone
Chapuy calcium and vitamin DThe New England journal of medicine 1992
Vitamin D3 and calcium to prevent hip fractures in elderly women
Supplementation significantly reduced hip fractures and other non-vertebral fractures, with correction of secondary hyperparathyroidism.
Randomised trialPreventionRheumatology & metabolic bone